Integrated DNA Technologies (IDT)

Integrated DNA Technologies sells short strands of DNA called oligonucleotides. In order to better understand how these are useful, you'll have to know a bit about DNA itself.

DNA is "the blueprint for life" and encodes instructions for all of life's processes. DNA is a complex long thin molecule (strand) that is made from 4 possible building blocks called "bases". These bases are called Adenine, Cytosine, Guanine and Thymine, and the precise order of these bases is a code for information. In living organisms, DNA strands can be millions of bases long and therefore contain huge amounts of information. This complexity is responsible for the vast complexity and diversity of life on earth.

The way that one strand of DNA specifically binds a second strand of DNA allows scientists to use short DNA strands (oligos) as research tools. A short synthetic piece of DNA (usually around 20 bases long) can be used to bind or find its matching sequence even in a complex mixture of millions of unrelated pieces of DNA. It is this unique fact that allows researchers to decode and study the genetic makeup of any living organism.

Using new oligo-based technologies, a revolution is underway where we are beginning to catalog the complete genetic makeup of hundreds of living things, ranging from bacteria to humans. The human genome alone contains over 3 billion bases of DNA, so projects of this kind tend to be very complex and often take years to complete.

Scientists often start the research knowing the DNA sequence for the organism that they are interested in studying. Given a known DNA sequence, they can easily design a short oligo that can be used to perform a variety of tasks. It is this short single-stranded DNA that the researcher orders from IDT. Living systems don't discriminate DNA that is synthesized chemically from DNA taken directly from an organism, allowing researchers to use IDT's custom made oligonucleotides as if they had existed naturally.

IDT manufactures the oligo using chemical DNA synthesis machines designed and built in-house. We've refined the process to the point where we can receive an order as late as 1:00pm and have the desired oligo in the researcher's hands the next morning. Our customers range from small university labs of only a few scientists to global pharmaceutical companies, and everything in between.

Some common uses for oligos include:

* Diagnostic tests for genetic diseases, like breast cancer or cystic fibrosis.
* Diagnostic tests for infectious diseases, like Hepatitis or AIDS.
* Research to discover new drugs or treatments for a variety of diseases.
* Producing safer and more plentiful agricultural products.

IDT is the largest manufacturer of custom oligo products in the US today. We became the industry leader in this competitive field by maintaining the highest standards of quality, service, and technical know-how.

Integrated DNA Technologies sells short strands of DNA called oligonucleotides. In order to better understand how these are useful, you'll have to know a bit about DNA itself.

DNA is "the blueprint for life" and encodes instructions for all of life's processes. DNA is a complex long thin molecule (strand) that is made from 4 possible building blocks called "bases". These bases are called Adenine, Cytosine, Guanine and Thymine, and the precise order of these bases is a code for information. In living organisms, DNA strands can be millions of bases long and therefore contain huge amounts of information. This complexity is responsible for the vast complexity and diversity of life on earth.

The way that one strand of DNA specifically binds a second strand of DNA allows scientists to use short DNA strands (oligos) as research tools. A short synthetic piece of DNA (usually around 20 bases long) can be used to bind or find its matching sequence even in a complex mixture of millions of unrelated pieces of DNA. It is this unique fact that allows researchers to decode and study the genetic makeup of any living organism.

Using new oligo-based technologies, a revolution is underway where we are beginning to catalog the complete genetic makeup of hundreds of living things, ranging from bacteria to humans. The human genome alone contains over 3 billion bases of DNA, so projects of this kind tend to be very complex and often take years to complete.

Scientists often start the research knowing the DNA sequence for the organism that they are interested in studying. Given a known DNA sequence, they can easily design a short oligo that can be used to perform a variety of tasks. It is this short single-stranded DNA that the researcher orders from IDT. Living systems don't discriminate DNA that is synthesized chemically from DNA taken directly from an organism, allowing researchers to use IDT's custom made oligonucleotides as if they had existed naturally.

IDT manufactures the oligo using chemical DNA synthesis machines designed and built in-house. We've refined the process to the point where we can receive an order as late as 1:00pm and have the desired oligo in the researcher's hands the next morning. Our customers range from small university labs of only a few scientists to global pharmaceutical companies, and everything in between.

Some common uses for oligos include:

Diagnostic tests for genetic diseases, like breast cancer or cystic fibrosis.
Diagnostic tests for infectious diseases, like Hepatitis or AIDS.
Research to discover new drugs or treatments for a variety of diseases.
Producing safer and more plentiful agricultural products.

IDT is the largest manufacturer of custom oligo products in the US today. We became the industry leader in this competitive field by maintaining the highest standards of quality, service, and technical know-how.

DNA & RNA Synthesis

Custom DNA Oligos
96- & 384-Well Plates
Ultramer DNA Oligos
Ultramer RNA Oligos
Custom RNA Oligos
SameDay Oligos
HotPlates
ReadyMade Primers
Oligo Modifications
Freedom Dyes
GMP for Molecular Diagnostics
Large Scale Oligo Synthesis

Optional Services

PAGE & HPLC Purification
Rapid HPLC Purification
Packaging & Formulation
Custom Tube Labeling
Preparative & Analytical Services
Mass Spectrometry & CE

Synthetic Biology

Synthetic Biology Overview
gBlocks Gene Fragments
Custom Gene Synthesis
Megamer ssDNA Fragments

Genome Editing

Genome Editing Overview
CRISPR-Cas9
CRISPR-Cpf1
CRISPR Nucleases

Functional Genomics

Functional Genomics Overview
DsiRNA and TriFECTa RNAi Kits
Antisense Oligonucleotides
miRNA Inhibitors

Genotyping

Genotyping Solutions Overview
rhAmp-Genotyping
LNA Probes
MGB Eclipse Probes and Primers

Next Generation Sequencing

Target Enrichment Solutions
Exome Research Panel
Human ID Research Panel
Human mtDNA Research Panel
AML Panel
Pan-Cancer Panel
Inherited Diseases Panel
Custom Probes & Panels
Blocking Oligos
Hybridization and Wash Kit
Target Capture Probe Design & Ordering Tool

Gene Expression

Probe-Based qPCR Master Mix
Probe-Based & Primer Only Assays
Predesigned qPCR Assays
Custom qPCR Probes
Molecular Beacons
PrimerQuest Tool
RealTime PCR Tool
GMP Probes and Primers

Reagents

Buffers & Solutions
Oligo Length Standards
Nuclease Detection Products
RNase H–Dependent PCR

Mutation Detection

Mutation Detection Overview
Alt-R Genome Editing Detection Kit
Surveyor Mutation Detection Kits

Business Services

Ordering Portals & Punch-outs
Custom OEM Manufacturing

Other

OligoCards