PolyMicrospheres

PolyMicrospheres offers research, development, and manufacturing of uniform polymer microspheres for clinical diagnostics, and microsphere- and nanoparticle-based drug delivery systems for pharmaceutical, medical device, and healthcare industries. Using state-of-the-art facilities and the most innovative polymerization and microencapsulation techniques, we develop and manufacture a complete range of microspheres and drug delivery systems with a variety of particle sizes and surface chemistries.

​Founded in 1990, PolyMicrospheres has cultivated its expertise in two main areas:

1.the development and precise manufacturing of very uniform microspheres for immunodiagnostic assays

2.the design and development of microsphere-based drug delivery systems for controlled release of pharmaceutical compounds over a period of weeks to months

Our expertise
With more than three decades of experience in polymer science, process engineering, and microparticle and drug delivery technologies, PolyMicrospheres has been at the forefront of microsphere development, microencapsulation, and controlled-release delivery systems.

Our product development group is led by Dr. Mohan, renowned for being a pioneer in microsphere development for over 30 years. He built the particle technology division at Seradyn (now ThermoFisher) in the late 1980s, developing the entire research and manufacturing programs from concept to commercialization. At PolyMicrospheres, he has further developed and optimized the processes and products to perfectly suit various immunodiagnostic and drug delivery applications.

The precision and accuracy of our techniques, together with GMP and ISO certified manufacturing practices, provide the highest quality and constantly reproducible products. With our extensive experience and expertise in microsphere development and manufacturing, you are always assured of a superior product, which performs the way it is designed to, batch after batch.

Our facilities
Our state-of-the-art facilities include:
•Modern and well-equipped labs and clean rooms
•Custom-designed glass/glass-lined reactors
•Precise process controllers (± 0.2°C and ± 1 rpm)
•Large-scale manufacturing (up to 300 liters of microspheres in a single production run)
•GMP and ISO certified manufacturing practices

Uniform Microspheres for Clinical Diagnostics

Product lines

Carboxyl
•10 product lines and over 150 products for covalent coupling
•The right particle size with correct level of COOH groups (50 to 300 µEq/g of carboxyl groups) for optimal coupling efficiency

Plain Surface
•7 product lines and over 100 products
•Optimized levels of sulfate groups for stabilization and best passive adsorption

Ready-to-Couple
•Ready-to-Couple Chloromethyl and Epoxy
•Preactivated and ready for easy one-step covalent coupling to amino groups
•High stability and long shelf life

Other
•Fluorescent and dyed microspheres
•Magnetic microparticles
•Large microbeads
•Particle size and calibration standards
•Microspheres for imaging, FPD, and LCD applications

Microsphere & Nanoparticle-based Drug Delivery Systems

Stemming from our microparticle expertise, PolyMicrospheres has been at the forefront of microencapsulation and advanced drug delivery technologies. Working with APIs from Eli Lilly, Merck, US Army, and others, we have developed drug delivery systems that provided the controlled-release of drugs and other bioactive agents for several weeks and even months.

​We specialize in the design and development of microsphere and nanoparticle-based drug delivery systems, including optimization, rapid feasibility stuides, evaluation and in vitro release studies, scale-up and manufacturing (from grams to kilogram quantities).